Last update :
08/11/2024
References   References 1230  
Type : Journal

Research teams : Oxford - The Churchill Hospital, Pharmacy Quality Control,
Authors : Regnard C, Pashley S, Westrope F.
Title : Anti-emetic / diamorphine mixture compatibility in infusion pumps.
Reference : Br J Pharm Pract ; 8: 218-220. 1986

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionCyclizine lactate Antihistamine (H1)
Compatible 7.5 mg/ml + injectionDiamorphine hydrochloride 7.5 mg/ml + None
Incompatible 3.125 >> 25 mg/ml + injectionDiamorphine hydrochloride 25 >> 112.5 mg/ml + None
injectionDiamorphine hydrochloride Analgesic
Compatible 7.5 mg/ml + injectionCyclizine lactate 7.5 mg/ml + None
Incompatible 25 >> 112.5 mg/ml + injectionCyclizine lactate 3.125 >> 25 mg/ml + None
Incompatible 45.45 >> 145.16 mg/ml + injectionHaloperidol lactate 0.16 >> 0.45 mg/ml + None
Compatible 18.18 mg/ml + injectionHaloperidol lactate 0.18 mg/ml + None
Compatible 45.45 >> 145.16 mg/ml + injectionMetoclopramide hydrochloride 0.16 >> 0.45 mg/ml + None
Compatible 49.6 >> 372.5 mg/ml + injectionScopolamine hydrobromide 0.001 >> 0.003 mg/ml + None
Compatible 41.67 >> 132.35 mg/ml + injectionScopolamine N-butyl bromide 2.35 >> 8 mg/ml + None
injectionHaloperidol lactate Neuroleptic
Incompatible 0.16 >> 0.45 mg/ml + injectionDiamorphine hydrochloride 45.45 >> 145.16 mg/ml + None
Compatible 0.18 mg/ml + injectionDiamorphine hydrochloride 18.18 mg/ml + None
injectionMetoclopramide hydrochloride Antiemetic
Compatible 0.16 >> 0.45 mg/ml + injectionDiamorphine hydrochloride 45.45 >> 145.16 mg/ml + None
injectionScopolamine hydrobromide Antimuscarinic
Compatible 0.001 >> 0.003 mg/ml + injectionDiamorphine hydrochloride 49.6 >> 372.5 mg/ml + None
injectionScopolamine N-butyl bromide Antimuscarinic
Compatible 2.35 >> 8 mg/ml + injectionDiamorphine hydrochloride 41.67 >> 132.35 mg/ml + None

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